Expression data from ferulic acid treated C. elegans

Gene expression in N2 worms treated with 500 µM or 0 µM ferulic acid, at days 5. Effects of ferulic acid in C. elegans gene expression is studied, as our results indicate a lifespan extension effect produced by this molecule. RNA-seq were used to detail the global programme of gene expression underlying the lifespan extension and identified distinct classes of up/down-regulated genes in animals treated with ferulic acid. Overall design: L4 C. elegans treated with ferulic acid for 5 days were selected for RNA extraction and RNA-seq

本数据集检测了经500微摩尔（µM）与0微摩尔阿魏酸处理的N2品系秀丽隐杆线虫在第5天的基因表达情况。本研究聚焦阿魏酸对秀丽隐杆线虫（C. elegans）基因表达的调控效应，前期实验结果显示该分子可延长线虫寿命。研究采用RNA测序（RNA-seq）技术，详细解析了阿魏酸介导线虫寿命延长背后的全局基因表达谱，并鉴定出阿魏酸处理组中显著上调与下调的不同基因类别。实验设计概要：将经阿魏酸处理5天的L4期秀丽隐杆线虫进行RNA提取，随后开展RNA-seq测序。