Mus musculus strain:KPC Transcriptome or Gene expression. Mus musculus strain:KPC

NIAID Data Ecosystem2026-03-08 收录

p53突变转录组

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA229893 数据链接链接失效反馈

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资源简介：

KPC (Comparing mutant-p53 expressing cells to knockdown cells)

KPC（对比表达突变型p53（mutant-p53）的细胞与敲低细胞的数据集）

创建时间：

2013-11-25

Expression analysis of Saos-2 cells expressing p53-His273

p53突变转录组

药物机制研究

Our compound (PRIMA) selectively kills tumor cells expressing mutant p53. Here in our study we decided to investigate the impact of our compound on the transcriptome of p53 mutant-expressing cells, Sa

NIAID Data Ecosystem60

Transcriptome analysis of mesenchymal CSC-like cells harboring mutant p53

干细胞分子机制

p53突变转录组

We show that mesenchymal CSC-like cells express an embryonic stem cell signature that is mutant p53 dependent Overall design: Examination of three p53 mutant mesenchymal stem cells and ten derived CSC

NIAID Data Ecosystem20

TP53 c.1000G>C; p.G334R is an Ashkenazi Jewish predominant mutation associated with a low penetrance Li-Fraumeni Syndrome. TP53 c.1000G>C; p.G334R is an Ashkenazi Jewish predominant mutation associated with a low penetrance Li-Fraumeni Syndrome

Li-Fraumeni综合征

p53突变转录组

Multiple family members with cancer or individuals with multiple primary cancers are indicative of potential genetic etiology1. Germline mutations in TP53 cause a rare high penetrance cancer syndrome,

NIAID Data Ecosystem20

Mutant p53 alters gene expression in human acute myeloid leukemia cells [patients]. Mutant p53 alters gene expression in human acute myeloid leukemia cells [patients]

急性髓系白血病分子特征

p53突变转录组

We found that Mutant p53 alters gene expression in human acute myeloid leukemia cells . Overall design: To determine whether mutant p53 alters gene transcription in human leuemia cells, we performed R

NIAID Data Ecosystem20

Mutant p53 dysregulates gene transcription in human CD34+ cells [RNA-seq 3]

p53突变转录组

造血干细胞基因表达

We found that mutant p53 alters gene transcription in human hematopoietic stem and progenitor cells (CD34+). Overall design: To determine the mechanisms by which mutant p53 enhances the repopulating p

NIAID Data Ecosystem20

Mus musculus strain:KPC Transcriptome or Gene expression. Mus musculus strain:KPC

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