Tuft cells restrain pancreatic tumorigenesis through paracrine eicosanoid signaling [bulk RNA-seq]. Tuft cells restrain pancreatic tumorigenesis through paracrine eicosanoid signaling [bulk RNA-seq]

We performed bulk RNA-seq on pancreatic and intestinal tuft cells, bone marrow derived macrophages with various treatments, and mouse pancreatic stellate cells with various treatments. Overall design: The transcriptomes of pancreatic and intestinal tuft cells, bone marrow derived macrophages, and pancreatic stellate cells were profiled. Three biological replicates for each cell type.

本研究对胰腺簇细胞与肠道簇细胞、经不同处理的骨髓来源巨噬细胞，以及经不同处理的小鼠胰腺星状细胞开展了批量RNA测序（bulk RNA-seq）。整体实验设计：对胰腺簇细胞、肠道簇细胞、骨髓来源巨噬细胞及胰腺星状细胞的转录组进行了测序分析；每种细胞类型设置3个生物学重复。