UCB-J PET and T1W Images for Synapse Project Cohort

# README
This dataset consists of (11-c) UCB-J PET and T1 Weighted (MPnRAGE_VFA : motion corrected) images. The cohort includes adults who are 60 years and above with a variety of clinical cognitive diagnoses including Alzheimer's Dementia, Mild Cognitive Impairment, and Normal cognition. All images are provided in native imaging space and have not been co-registered to a common space.

## Details related to the T1 Images
### MPnRAGE_VFA : motion corrected
The resolution is 1mm isotropic. The aquisition parameters are as follows:
"EchoTime": 0.00182,
"RepetitionTime": 0.004876,
"FlipAngle": 4,
"ShimSetting": [
8,
12,
-37]

These two seminal papers describe the theory and methodology of the T1-weighted MPnRAGE sequence: https://pmc.ncbi.nlm.nih.gov/articles/PMC6192848/ and https://pmc.ncbi.nlm.nih.gov/articles/PMC8525331/#R13

## Details related to the UCB-J Images
A target dose of 5-15 mCi +/- 10% of UCB-J bolus is injected over ~30 second infusion with the participant positioned in the scanner. A 70 minute dynamic PET scan was initiated with the injection of radiotracer.

# 数据集说明
本数据集包含11-c队列的正电子发射计算机断层显像（Positron Emission Tomography，PET）成像与T1加权成像（T1 Weighted Imaging）图像，其中T1加权成像采用运动校正的MPnRAGE_VFA序列。该队列纳入60岁及以上的成年受试者，临床认知诊断涵盖阿尔茨海默病性痴呆（Alzheimer's Dementia）、轻度认知障碍（Mild Cognitive Impairment）及认知正常人群。所有图像均保留于原始成像空间，未配准至公共标准空间。

## T1成像相关细节
### MPnRAGE_VFA：运动校正
该图像的分辨率为1mm各向同性。具体采集参数如下：
"回波时间（EchoTime）": 0.00182,
"重复时间（RepetitionTime）": 0.004876,
"翻转角（FlipAngle）": 4,
"匀场设置（ShimSetting）": [
8,
12,
-37
]

以下两篇开创性研究论文详细阐述了T1加权MPnRAGE序列的理论与方法：https://pmc.ncbi.nlm.nih.gov/articles/PMC6192848/ 与 https://pmc.ncbi.nlm.nih.gov/articles/PMC8525331/#R13

## UCB-J成像相关细节
受试者被安置于扫描仪内时，以约30秒的输注时长注射目标剂量为5~15毫居里（mCi，误差范围±10%）的UCB-J弹丸式放射性示踪剂。于注射放射性示踪剂的同时启动时长70分钟的动态PET扫描。