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A framework to identify antigen-expanded T Cell Receptor (TCR) clusters within complex repertoires

NIAID Data Ecosystem2026-03-13 收录

免疫组库分析

TCR克隆扩增检测

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP331659 数据链接链接失效反馈

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资源简介：

A novel framework for detection of antigen-expanded TCRs.

面向抗原扩增T细胞受体（TCR）检测的新型框架

应用场景：

创建时间：

2021-12-20

免疫组库分析

疫苗免疫学

Application of high-throughput DNA sequencing of the IGH gene rearrangements to study the B cell repertoires over two successive years in 27 individuals ranging in age from 20 to 89 years old.

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COVID-19-IRST/AUSL: We describe the establishment and current content of the ImmuneCODE™ database, which includes hundreds of millions of T-cell Receptor (TCR) sequences from over 1,400 subjects expos

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tcr_beta_synrep_set2_01.txt.bz2

T细胞受体库

免疫组库分析

Synthetic T cell receptor beta chain repertoire generated using IGoR software. Record format: V-gene D-gene J-gene amino-acid-CDR3 Where CDR3 contains anchor residues (V-gene Cys, J-gene Ph

Figshare2020-06-03 更新20

454 libraries of PCR products for T cell receptors in regulatory and conventional CD4-expressing T lymphocytes. Mus musculus

T细胞受体库

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Fractions of the T cell repertoire of wild type (WT) mice or mice engineered for fixing their TCR β chain by somatic cloning (1D2b) or transgenesis (Vb3Tg) were characterised by sequencing α or β full

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Characterizing adjuvants' effects at the murine immunoglobulin repertoire level

免疫组库分析

疫苗佐剂评价

We developed an improved library prep protocol and standardized the data analysis pipeline for accurate repertoire profiling. In addition, two metrics were implemented to assess repertoire clone prope

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A framework to identify antigen-expanded T Cell Receptor (TCR) clusters within complex repertoires

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