Summary of clinical characteristics for 121 patients with EM and association of the significance of spirochete number with clinical characteristic.

aAs determined by Mann-Whitney test.bSystemic symptoms comprised fatigue, headache, myalgia, arthralgia, malaise, rigors, dizziness, nausea and fever.cSymptoms at site comprised itching, burning and pain.dHistory of extracutaneous LB and/or EM, previously diagnosed by a physician; data not available for 1 patient (i.e.) n = 120.eChronic underlying illness; arterial hypertension, hyperlipidemia, osteoporosis, diabetes mellitus, thyroid disease, cardiac rhythm abnormality, psychiatric illness, ischemic heart disease, osteoarthritis or asthma.fPatients had malignancy and were treated with chemo−/radiotherapy within the last year.

a. 经曼-惠特尼检验（Mann-Whitney test）确定。
b. 全身症状涵盖疲劳、头痛、肌痛、关节痛、全身不适、寒战、头晕、恶心及发热。
c. 局部症状包括瘙痒、灼烧感与疼痛。
d. 既往经医师确诊的皮肤外莱姆病（extracutaneous LB）和/或慢性游走性红斑（EM）病史；1名患者无相关数据，即有效样本量n=120。
e. 慢性基础疾病：包括动脉高血压、高脂血症、骨质疏松症、糖尿病、甲状腺疾病、心律异常、精神疾病、缺血性心脏病、骨关节炎及哮喘。
f. 患者罹患恶性肿瘤，且于过去1年内接受过化疗及/或放疗。