Paper memory neural words

The goal of the present study was to investigate whether exposing individuals with MDD to negative cues during the encoding stage would lead to deeper cognitive processing and improved memory retention of subsequent information. We hypothesized that in the MDD group, exposure to the negative prime cue would result in better recall of the subsequent word list compared to exposure to the positive prime cue. Furthermore, we predicted that the impact of the emotional prime cue on memory recall would be more pronounced when presented during the encoding stage compared to the retrieval stage. For the encoding condition, in the MDD group we found a significant difference indicating better word recalling for the negative compared to the positive video valance condition. In the HC group there was no significant difference between the two video valence conditions. For the retrieval condition, the results revealed no video valence X group interaction. Consistent with assumptions, individuals with MDD, but not HCs, showed enhanced word recall after exposure to negative, compared to positive, emotional stimuli during encoding. Notably, this effect was not observed when the emotional video was presented during the retrieval stage

本研究旨在探讨在编码阶段向重度抑郁症（Major Depressive Disorder, MDD）患者呈现负性线索，是否可引发更深层次的认知加工，并提升其对后续信息的记忆保持能力。我们提出如下假设：相较于正向启动线索，负向启动线索的暴露可使MDD组受试者对后续单词表的回忆表现更优异。进一步预测：情绪启动线索在编码阶段呈现时，对记忆回忆的影响将较其在提取阶段呈现时更为显著。针对编码条件，MDD组的结果存在显著差异，即负向视频效价条件下的单词回忆表现优于正向视频效价条件；而健康对照组（Healthy Controls, HC）的两种视频效价条件间无显著差异。针对提取条件，结果显示视频效价与组别间不存在交互效应。与研究假设一致，仅MDD患者在编码阶段接触负向情绪刺激后，单词回忆表现较正向情绪刺激组有所提升，健康对照组则未观察到该效应。值得注意的是，当情绪视频于提取阶段呈现时，未发现此类效应。