Omics-Lethal Human Viruses, MERS-CoV Experiment MMVE001

The purpose of this experiment was to evaluate the human host response to wild-type Middle Eastern Respiratory Syndrome coronavirus (icMERS-CoV) virus infection. Sample data was obtained from human microvascular endothelial cells for mRNA, miRNA, proteomics, lipidomics, and metabolomics expression analysis. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Leveraging unique high-resolution Omics capabilities for proteomics, metabolomics, lipidomics, and transcriptomics dataset downloads each have a direct relationship to a primary sample submission corresponding to a specific MERS-CoV virus infection.

本实验旨在评估人类宿主对野生型中东呼吸综合征冠状病毒（icMERS-CoV）的感染应答。本实验的样本数据取自人类微血管内皮细胞，用于信使RNA（mRNA）、微小RNA（miRNA）、蛋白质组学、脂质组学及代谢组学的表达分析。附带下载的宿主相关病毒次级数据集，包含经统计学处理（归一化与数据转换）的定量数据集合集，可用于原发性宿主-病原体实验研究设计的定性表达分析。所有依托独特高分辨率组学（Omics）技术获取的蛋白质组学、代谢组学、脂质组学及转录组学数据集下载资源，均与对应特定MERS-CoV感染的原样本提交数据存在直接关联。