Global transcriptional profiling of HCC827 lung adenocarcinoma cells in response to EGFR inhibition

mRNA sequencing of EGFR mutant HCC827 lung adenocarcinoma cells were treated with erlotinib (EGFR inhibitor) for 24hr to profile and characterize dysregulated pathways in response to EGFR inhibition HCC827 cells treated with 24h erlotinib or DMSO control in a 3 vs 3 sample design

本数据集针对经厄洛替尼（EGFR抑制剂）处理24小时的EGFR突变型HCC827肺腺癌细胞开展mRNA测序，以解析并表征EGFR抑制诱导的失调信号通路；实验采用3例厄洛替尼处理组与3例二甲基亚砜（DMSO）对照组的样本设计。