The cryo-EM structure of human Piezo2-MDFIC2 complex (composite map)

The cryo-EM structure of human Piezo2-MDFIC2 complex (composite map) Descriptor: MyoD family inhibitor domain-containing protein 2, Piezo-type mechanosensitive ion channel component 2,Green fluorescent protein Authors: Zhang, Y, Dai, F, Zhou, Z, Dai, F, Cheng, D, Ma, X, Omidkhoda, S.F, Clarke, J, Zhang, H, Laden, M, Guo, Y, Li, J.V, Liu, R, Wong, E.S, Zhang, Y, Cox, C.D. Deposit date: 2025-06-09 Release date: 2026-04-08 Last modified: 2026-05-06 Method: ELECTRON MICROSCOPY (3.36 Å) Cite: MDFIC2 is a sensory neuron-specific PIEZO channel auxiliary subunit Proc.Natl.Acad.Sci.USA, 2026人类Piezo2-MDFIC2复合物的冷冻电镜（cryo-EM）结构（复合图谱） 描述符：MyoD家族抑制域包含蛋白2（MyoD family inhibitor domain-containing protein 2）、Piezo型机械敏感性离子通道组分2（Piezo-type mechanosensitive ion channel component 2）、绿色荧光蛋白（Green fluorescent protein） 作者：Zhang Y、Dai F、Zhou Z、Dai F、Cheng D、Ma X、Omidkhoda S.F、Clarke J、Zhang H、Laden M、Guo Y、Li J.V、Liu R、Wong E.S、Zhang Y、Cox C.D. 提交日期：2025-06-09 发布日期：2026-04-08 最后修改日期：2026-05-06 方法：电子显微镜（3.36埃） 引用：MDFIC2为感觉神经元特异性PIEZO通道辅助亚基，《美国国家科学院院刊（Proceedings of the National Academy of Sciences of the United States of America）》，2026年