Functional properties of Candida albicans extracellular vesicles released in the presence of antifungal drugs, amphotericin B, fluconazole and caspofungin - research data

Dataset underlying the publication "Functional properties of Candida albicans extracellular vesicles released in the presence of the antifungal drugs amphotericin B, fluconazole and caspofungin". DOI 10.1099/mic.0.001565. Raw data for Figure 1. Release of EVs by C. albicans cells cultured in the presence of antifungal drugs, amphotericin B (AMB), fluconazole (FLU) or caspofungin (CASP). Raw data for Figure 2. The change in EVs production by fungal cells grown in the presence of antimycotic drugs, amphotericin B (AMB), fluconazole (FLU) or caspofungin (CASP). Raw data for Figure 3 Characteristics of EVs produced by C. albicans. Average particle size (mode) determined by Nanoparticle Tracking Analysis (NTA) from two histograms with the particle size distribution obtained after three measurements of each sample. Raw data for Figure 4. Composition of C. albicans EVs. Raw data for Figure 5. The impact of C. albicans EVs on tolerance to antifungals. Formation of C. albicans biofilm in the presence of the antifungal drugs, amphotericin B (AMB), fluconazole (FLU) and caspofungin (CASP) and fungal EVs. Raw data for Figure 6. The changes of zeta potential of liposomes or U-937 cells in response to C. albicans EVs. Raw data for Figure 7. The THP-1 host cells response to C. albicans EVs. Raw data for Figure 8. The impact of EVs on the survival of G. mellonella larvae and activity of phenol oxidase in hemolymph.

本数据集为发表论文《暴露于抗真菌药物两性霉素B（amphotericin B, AMB）、氟康唑（fluconazole, FLU）和卡泊芬净（caspofungin, CASP）的白色念珠菌（Candida albicans, C. albicans）胞外囊泡（extracellular vesicles, EVs）的功能特性》提供原始数据，DOI: 10.1099/mic.0.001565。
图1原始数据：在抗真菌药物两性霉素B（AMB）、氟康唑（FLU）或卡泊芬净（CASP）培养条件下，白色念珠菌（C. albicans）细胞释放胞外囊泡（EVs）的相关数据。
图2原始数据：暴露于抗真菌药物两性霉素B（AMB）、氟康唑（FLU）或卡泊芬净（CASP）的真菌细胞，其胞外囊泡产量变化的相关数据。
图3原始数据：白色念珠菌（C. albicans）产生的胞外囊泡的特性数据，包括通过纳米颗粒追踪分析（Nanoparticle Tracking Analysis, NTA）测定的平均粒径（众数），该数据取自两份直方图，每份样本经三次测量后得到粒径分布结果。
图4原始数据：白色念珠菌（C. albicans）胞外囊泡的组成成分相关数据。
图5原始数据：白色念珠菌（C. albicans）胞外囊泡对抗真菌药物耐受性的影响相关数据，以及在抗真菌药物两性霉素B（AMB）、氟康唑（FLU）、卡泊芬净（CASP）与真菌胞外囊泡共同存在时，白色念珠菌生物膜形成的相关数据。
图6原始数据：白色念珠菌（C. albicans）胞外囊泡作用下，脂质体或U-937细胞的ζ电位（zeta potential）变化相关数据。
图7原始数据：THP-1宿主细胞对白色念珠菌（C. albicans）胞外囊泡的应答反应相关数据。
图8原始数据：胞外囊泡对大蜡螟（G. mellonella）幼虫存活率以及血淋巴中酚氧化酶活性的影响相关数据。