Omics-Lethal Human Viruses, Ebola Experiment EHUH002

The purpose of this experiment was to evaluate the human host response to Zaire Ebola wild-type virus and mutant virus infection. Samples were obtained from human hepatoma carcinoma cells (HUH-7) infected with Zaire Ebola ΔVP30-WT background for proteome, metabolome, and lipidome expression analysis. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Leveraging unique high-resolution Omics capabilities for proteomics, metabolomics, and lipidomics dataset downloads each have a direct relationship to a primary sample submission corresponding to a specific Ebola virus infection.

本实验旨在评估人类宿主对扎伊尔埃博拉野生型病毒与突变病毒感染的应答反应。实验样本取自感染扎伊尔埃博拉ΔVP30-WT背景病毒的人类肝癌细胞（HUH-7），用于蛋白质组（proteome）、代谢组（metabolome）及脂质组（lipidome）的表达分析。供下载的宿主相关病毒二级数据集包含一个或多个经统计处理（归一化与数据转换）的定量数据集合集，可用于原代宿主-病原体实验研究设计的定性表达分析。依托蛋白质组学、代谢组学及脂质组学的高分辨率组学（Omics）独有技术能力，各类下载数据集均与对应特定埃博拉病毒感染的原代样本提交存在直接关联。