Identifying Lsr2 binding sites in Streptomyces venezuelae. Identifying Lsr2 binding sites in Streptomyces venezuelae

The goal of this work was to determine where Lsr2 binds within the S. venezuelae chromosome, and to differentiate between direct versus indirect effects by comparing our ChIP-seq results with RNA-seq results Overall design: S. venezuelae ChIP-seq data, generated using an Illumina MiSeq platform

本研究旨在明确Lsr2蛋白在委内瑞拉链霉菌（S. venezuelae）染色体上的结合位点，并通过将本研究的染色质免疫共沉淀测序（ChIP-seq）结果与RNA测序（RNA-seq）结果进行比对，区分直接与间接基因调控效应。实验整体设计：采用Illumina MiSeq测序平台生成的委内瑞拉链霉菌（S. venezuelae）ChIP-seq数据。