Regulation of Pkm2 by miR-122.
收藏NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE29907
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资源简介:
The study identified Pkm2 to be highly expressed in human embryonic stem cells and hepatocellular carcinoma cells, and targeted by a microRNA that is highly expressed in human primary hepatocytes. Gene expression patterns were compared from total RNA obtained from human embryonic stem cells, human primary hepatocytes, and hepG2 and hep3B.
本研究证实,丙酮酸激酶M2(Pkm2)在人类胚胎干细胞与肝细胞癌细胞中呈高表达,且可被一种在人原代肝细胞中高表达的微小RNA(microRNA)靶向调控;同时,本研究对取自人类胚胎干细胞、人原代肝细胞以及HepG2与Hep3B细胞的总RNA开展了基因表达谱对比分析。
创建时间:
2017-03-20



