Dataset related to the article "Ventricular tachycardia ablation with pentaspline pulsed field technology in two patients with ischemic cardiomyopathy""

This record contains raw data related to the article "Ventricular tachycardia ablation with pentaspline pulsed field technology in two patients with ischemic cardiomyopathy" 

Abstract

Introduction: Due to its unique features, pulsed field ablation (PFA) could potentially overcome some limitations of current radiofrequency (RF) ventricular tachycardia (VT) ablation. However, data on the use of PFA in this setting are currently scarce.

Methods: Two patients with ischemic cardiomyopathy and previously failed RF VT ablations were treated with PFA.

Results: A total of 18 bipolar applications (case1) and seven bipolar applications (case2) were delivered to the infero-lateral and infero-septal areas (case1) and to the apical lateral left ventricular (LV) wall (case2), placing the catheter adjacent to the LV wall in the flower configuration. A rapid cessation of VT and restoration of sinus rhythm were observed during PFA delivery in both cases. Further applications were delivered to achieve complete elimination of late potentials. In case 1, during the in-hospital stay, ECG monitoring did not show VT recurrences. Six-month follow-up was uneventful, with no VT recurrences at ICD interrogation. In case 2, due to postdischarge VT recurrences, a second RF procedure was scheduled 1 month later. The voltage map performed in sinus rhythm showed a low-voltage zone located at the anterolateral wall, near the previous ablation site. Numerous late potentials were recorded. At the 6-month follow-up, no further VT recurrences were documented after RF redo ablation.

Conclusion: While the speed of application and potential transmural effect can facilitate the ablation of large diseased endocardial areas, early loss of contact due to difficult pentaspline catheter manipulation in the LV could lead to insufficient contact force and, consequently, inadequate energy penetration.

Keywords: ischemic cardiomyopathy; pulsed field ablation; radiofrequency; scar‐related; ventricular tachycardia.

This dataset is not public. It’s available upon reasonable requesto to the [e-mail].

本数据集包含与论文《两例缺血性心肌病患者采用五分体式脉冲场技术行室性心动过速消融术》相关的原始数据。

摘要

引言：脉冲场消融（pulsed field ablation, PFA）凭借其独特的性能，有望克服当前射频消融（radiofrequency, RF）治疗室性心动过速（ventricular tachycardia, VT）所存在的部分局限。但目前针对该场景下PFA应用的相关研究数据仍较为匮乏。

方法：本研究纳入2例既往行射频消融室性心动过速治疗失败的缺血性心肌病（ischemic cardiomyopathy）患者，采用脉冲场消融技术进行治疗。

结果：病例1共对下外侧及下间隔区域实施18次双极能量递送，病例2则对左心室（left ventricular, LV）心尖外侧壁实施7次双极能量递送，术中采用花形构型将导管贴靠于左心室壁。两例患者在脉冲场消融过程中均观察到室性心动过速快速终止并恢复窦性心律。后续追加能量递送以彻底消除晚电位。病例1住院期间心电监护未提示室性心动过速复发；术后6个月随访时，植入式心律转复除颤器（ICD）程控未发现室性心动过速复发。病例2患者出院后出现室性心动过速复发，于1个月后接受二次射频消融手术。术中窦性心律下的电压标测显示，前外侧壁靠近既往消融位点处存在低电压区域，且记录到大量晚电位。术后6个月随访显示，二次射频消融后未再出现室性心动过速复发。

结论：尽管脉冲场消融的操作速度及潜在的透壁效应可便于对大面积病变心内膜区域进行消融，但左心室内五分体式导管（pentaspline catheter）操作难度较大可能导致早期贴靠丢失，进而造成接触压力不足，最终使能量渗透不充分。

关键词：缺血性心肌病；脉冲场消融；射频消融；瘢痕相关性；室性心动过速。

本数据集尚未公开，如有合理需求可发送邮件至[e-mail] 申请获取。