Results of the predicted contributions of residues through virtual alanine scanning.

Note: Chain A, hTLR2; Chain B, hTLR1; Chain D, hTLR10; Chain E, hTLR10*; PDB, position of mutated residues in the pdb file; ΔΔGbind, predicted change in binding free energy upon alanine mutation.

备注：A链为人类Toll样受体2（hTLR2）；B链为人类Toll样受体1（hTLR1）；D链为人类Toll样受体10（hTLR10）；E链为人类Toll样受体10变体（hTLR10*）；PDB指代该PDB文件中突变残基的位置；ΔΔGbind为丙氨酸突变后的结合自由能预测变化量。