Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor TAMU-A7)

Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor TAMU-A7) Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 4,4,4-trifluoro-1-(4-methoxyphenyl)butane-1,3-dione, Anthranilate phosphoribosyltransferase, ... Authors: Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC) Deposit date: 2011-02-20 Release date: 2012-08-22 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Inhibition of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase by blocking of an active site entrance tunnel. To be Published

结核分枝杆菌（Mycobacterium tuberculosis）来源的邻氨基苯甲酸磷酸核糖转移酶（Anthranilate phosphoribosyltransferase，trpD，与抑制剂TAMU-A7形成复合物）。描述物：1-O-焦膦酰基-5-O-膦酰基-α-D-呋喃核糖、4,4,4-三氟-1-(4-甲氧基苯基)丁烷-1,3-二酮、邻氨基苯甲酸磷酸核糖转移酶……作者：Castell, A、Short, F.L、Lott, J.S及TB结构基因组学联盟（TB Structural Genomics Consortium, TBSGC）。存放日期：2011-02-20；发布日期：2012-08-22；最后修改日期：2024-02-21。实验方法：X射线衍射（分辨率2.18埃）。引用文献：《通过阻断活性位点入口隧道抑制结核分枝杆菌邻氨基苯甲酸磷酸核糖转移酶》，待发表。