LCVD: Low-cost cell-extract viral diagnostics

The datasets contain measurements performed using a configurable colorimetric readout set-up for automated readout from lateral flow test strips.The readout set-up consists of a 3D-printed enclosure device with detector module electronics contained inside, along with a mechanism into which a lateral flow test strip can be inserted. The set-up can be adjusted in x, y and z directions to allow for accurate positioning, alignment and optimization of measurements performed on both model and real lateral flow test strips. Lateral flow test strips can be analysed both without a cartridge housing or within a cartridge housing. The dataset contains the raw measurements and results of the data obtained from the generic test set-up for various configurations of test set-up and the lateral flow test strips analysed. This dataset encompasses various datasets and results obtained during my PhD entitled: Wireless colorimetric readout for resource-limited point-of-care.The work details a hybrid printed and packaged low-cost wireless color detector device. By combining the growing fields of paper-based diagnostics and printed electronics with Southern African clinic perspectives, a scalable, low cost, paper-based solution for result readout and communication was developed.Printed radio frequency identification devices with sensing capabilities were manufactured onto different low-cost and paper-based substrates to assess the practicalfunctionality of these devices. Extensive images and results pertaining to this are included in this dataset.This work was further extended to target colour detection from lateral flow test strip devices and other typical paper-based rapid test formats. The results were comparedto those obtained from manual readout using colour charts, a commercial lateral flow test strip reader and image analysis using ImageJ.

本数据集包含采用可配置比色读出装置获取的测量数据，该装置用于实现侧向流检测试纸条（lateral flow test strip）的自动化读数。该读出装置由内部集成探测器模块电子元件的3D打印外壳装置，以及可插入侧向流检测试纸条的夹持机构构成。该装置可沿x、y、z三个轴向调节，以实现对模型及实物侧向流检测试纸条的测量进行精准定位、校准与优化。侧向流检测试纸条可在无试剂盒外壳或搭载试剂盒外壳的两种场景下完成分析。本数据集包含从通用测试装置获取的原始测量数据与分析结果，覆盖多种测试装置配置及待分析的侧向流检测试纸条类型。
本数据集涵盖了本人题为《面向资源受限场景的即时检测无线比色读出技术》（Wireless colorimetric readout for resource-limited point-of-care）的博士研究期间获取的各类数据集与分析结果。该项研究开发了一种混合打印封装的低成本无线比色探测装置：将纸基诊断与印刷电子领域的前沿进展与南非诊所的实际需求相结合，研发出了一套可规模化应用的低成本纸基结果读出与传输解决方案。
研究人员将带传感功能的印刷射频识别（radio frequency identification, RFID）器件制备于多种低成本纸基衬底上，以评估该类器件的实际功能，相关的大量图像与实验结果均收录于本数据集。该项研究进一步拓展至侧向流检测试纸条及其他典型纸基快速检测格式的颜色探测领域，并将实验结果与三种常规读数方式的结果进行了对比：基于色卡的人工读数、商用侧向流检测试纸条读数仪，以及采用ImageJ软件的图像分析法。