Flicr, a long noncoding RNA modulating Foxp3 expression and autoimmunity (ATAC-Seq)

ATAC-seq profiles of Tregs isolated from spleen and LN in Flicr WT and KO mice DAPI-CD4+TCRb+ CD25hi (top 50%) Tregs were single sorted from the spleen and LN of male NOD mice and ATAC-seq was performed

本数据集包含Flicr基因野生型（WT）与敲除型（KO）小鼠脾脏及淋巴结（LN）中分离的调节性T细胞（Tregs）的转座酶可及性染色质测序（ATAC-seq）图谱。实验中，从雄性非肥胖糖尿病（NOD）小鼠的脾脏与淋巴结中，分选得到4',6-二脒基-2-苯基吲哚（DAPI）阴性、CD4阳性、TCRβ阳性且CD25高表达（占比前50%）的调节性T细胞，经单细胞分选后开展ATAC-seq实验。