A genome-wide screening identified effector genes of chromatin accessibility. To investigate the functional consequences of the loss of each effector gene, we conducted Mnase-seq with eHAP cells knock

NIAID Data Ecosystem30

ATAC-seq

染色质可及性分析

造血干细胞分化表观遗传学

The chromatin remodeller ATRX interacts with the histone chaperone DAXX, to deposit the histone variant H3.3 at sites of nucleosome turnover. ATRX is known to bind repetitive, heterochromatic regions

NIAID Data Ecosystem20

Chromatin accessibility analysis of induced trophoblast stem cells.

诱导滋养干细胞

染色质可及性分析

We report chromatin accessibility time-course profiling (ATAC-seq) of induced trophoblast stem cells (iTSCs) derived directly from human fibroblasts and naÃ¯ve reprogramming intermediates. Overall des

NIAID Data Ecosystem40

Sequence determinants of human gene regulatory elements, ATAC-seq experiments

基因调控元件序列决定因素

染色质可及性分析

DNA determines where and when genes are expressed, but the full set of sequence determinants that control gene expression is not known. Here, we measured transcriptional activity of DNA sequences that

NIAID Data Ecosystem30

Angiogenic open chromatin regions

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