Brain and mitochondrial Aβ levels were not changed in ischemic 5xFAD mice.

The levels of brain (A) and mitochondrial (B) Aβ1–40 and Aβ1–42 remained unchanged in sham-operated and ischemic 5xFAD mice. The intensity (C) and occupied area (%) (D) of Aβ plaques in cortex or hippocampus in sham-operated and ischemic 5xFAD mice were not altered. (E) Representative images of Aβ staining. Scale bar = 500 μm. N = 3–4 mice of each group.假手术组与缺血性5xFAD小鼠的脑组织（A）及线粒体（B）中Aβ₁₋₄₀与Aβ₁₋₄₂的水平均未发生显著变化。假手术组与缺血性5xFAD小鼠大脑皮层或海马体中的Aβ斑块强度（C）及占据面积百分比（D）均无明显改变。(E) Aβ染色的代表性图像，比例尺=500 μm。每组小鼠的样本量为3~4只。