Co-crystal structure of Chaetomium glucosidase with compound 16
收藏Protein Data Bank Japan2024-10-30 更新2026-04-25 收录
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Co-crystal structure of Chaetomium glucosidase with compound 16 Descriptor: (2R,3R,4R,5S)-2-(hydroxymethyl)-1-{[4-({2-nitro-4-[(1R,5S)-3-oxa-8-azabicyclo[3.2.1]octan-8-yl]anilino}methyl)phenyl]methyl}piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chaetomium alpha glucosidase, ... Authors: Karade, S.S, Mariuzza, R.A. Deposit date: 2022-09-23 Release date: 2023-02-22 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum alpha-Glucosidase I with Anti-SARS-CoV-2 Activity. J.Med.Chem., 66, 2023
毛壳菌（Chaetomium）α-葡糖苷酶与化合物16的共晶体结构
描述符：(2R,3R,4R,5S)-2-(羟甲基)-1-{[4-({2-硝基-4-[(1R,5S)-3-氧杂-8-氮杂双环[3.2.1]辛烷-8-基]苯胺基}甲基)苯基]甲基}哌啶-3,4,5-三醇、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、毛壳菌α-葡糖苷酶……
作者：Karade, S.S.、Mariuzza, R.A.
存储日期：2022-09-23
发布日期：2023-02-22
最后修改日期：2024-10-30
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.6 Å
引用文献：《具有抗SARS-CoV-2活性的内质网α-葡萄糖苷酶I强效亚氨基糖抑制剂的基于结构设计》，J.Med.Chem., 66, 2023
创建时间：
2022-09-23
