Tmem203 null male mice are sterile.

Uninterrupted mating was performed between sexually mature (aged 8 weeks old) Tmem203 null (tmem203 -/-), heterozygous (tmem203 -/+) and wild type (tmem203 +/+) mice for 17 weeks. All litters and litter sizes were recorded for each mating pair.Tmem203 null male mice are sterile.对8周龄性成熟的Tmem203基因敲除（Tmem203 null，tmem203⁻/⁻）、杂合型（tmem203⁻/+）及野生型（tmem203⁺/⁺）小鼠开展为期17周的不间断交配实验，记录每一组交配对的所有产仔情况与每窝幼崽的数量。实验发现，Tmem203基因敲除的雄性小鼠不育。