Stenotrophomonas geniculata strain:MLIP23 Genome sequencing

Nosocomial infections caused by different microorganisms generate a high mortality rate in patients who are mainly in the hospital intensive care unit. Stenotrophomonas geniculata Sg_MLIP23 is attributed to 37.5% of mortality in hospitals, generally, all clinical isolates have shown that they are genotypically and phenotypically very diverse, which gives it a certain advantage to infect patients. The disease caused by COVID-19 caused nosocomial infections, to and played an important role in increasing the mortality rate in patients in intensive care. The isolation, sequencing, and assembled genome of S. geniculata consisted of 4,488,090 bp in 24 contigs, with 4,103 coding sequences and G+C content of 66.58%.

由不同微生物引发的医院感染（Nosocomial infections），会在以医院重症监护病房（intensive care unit, ICU）患者为主的群体中造成较高的病死率。膝状寡养单胞菌（Stenotrophomonas geniculata）Sg_MLIP23与医院内37.5%的死亡病例相关；现有研究显示，所有临床分离株均具有显著的基因型与表型多样性，这为其感染宿主患者提供了一定的竞争优势。由新型冠状病毒肺炎（COVID-19）引发的病症可诱发医院感染，同时也是加剧重症监护病房患者病死率上升的关键因素之一。本研究分离、测序并组装的膝状寡养单胞菌（S. geniculata）基因组全长为4488090 bp，由24个重叠群（contigs）构成，包含4103个编码序列，G+C含量为66.58%。