遇见数据集

Associations of <i>JAZF1</i> SNP rs864745, <i>CDC123/CAMK1D</i> SNP rs12779790, and <i>TSPAN8/LGR5</i> SNP rs7961581 with anthropometrics, insulin sensitivity, and insulin secretion (N = 1578).

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NIAID Data Ecosystem2026-03-06 收录
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Data represent means±SD. For statistical analysis, data were log-transformed. Age was adjusted for gender. BMI, body fat, and waist circumference were adjusted for gender and age. Plasma glucose levels and indices of insulin sensitivity were adjusted for gender, age, and BMI. Indices of insulin secretion were adjusted for gender, age, BMI, and ISI (OGTT). p1–p-value, additive model; p2–p-value, dominant model. AUC–area under the curve; HOMA-IR–homeostasis model assessment of insulin resistance; ISI–insulin sensitivity index; MAF–minor allele frequency; SNP–single nucleotide polymorphism. *subgroup (N = 513).

数据以均值±标准差(standard deviation, SD)表示。统计学分析前,对数据实施对数转换。年龄已针对性别因素进行校正;体重指数(Body Mass Index, BMI)、体脂率及腰围已按性别与年龄进行校正;血浆葡萄糖水平与胰岛素敏感性指标已按性别、年龄及BMI进行校正;胰岛素分泌指标已按性别、年龄、BMI及口服葡萄糖耐量试验(oral glucose tolerance test, OGTT)中的胰岛素敏感性指数(insulin sensitivity index, ISI)进行校正。p1为加性模型的p值,p2为显性模型的p值。相关术语说明如下:曲线下面积(area under the curve, AUC)、胰岛素抵抗稳态模型评估(homeostasis model assessment of insulin resistance, HOMA-IR)、胰岛素敏感性指数(ISI)、次要等位基因频率(minor allele frequency, MAF)及单核苷酸多态性(single nucleotide polymorphism, SNP)。*亚组(N=513)。

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2008-08-20
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