Corynebacterium sp. 335C isolate:C335C Genome sequencing. Corynebacterium sp. 335C isolate:C335C

Although accurate classification of the Corynebacterium species in clinical isolates is important for selecting aappropriate treatment due to unfavorable resistance profile of many different species (such as Corynebacterium amycolatum, Corynebacterium jeikeium and Corynebacterium urealyticum), several strains still characterized only to the genus level due to problematic phenotypic identification of non-diphtheriae Corynebacteria. New research studies in this line would, thus, increase our knowledge of fundamental aspects of the whole genus, while comparisons between different corynebacterial species can disclosed virulence genes and aid in understanding the pathogenicity.

鉴于多种棒杆菌属（Corynebacterium）物种（如无枝酸棒杆菌（Corynebacterium amycolatum）、杰氏棒杆菌（Corynebacterium jeikeium）和解脲棒杆菌（Corynebacterium urealyticum））均具有不良的耐药谱，因此对临床分离株中的棒杆菌物种进行精准分类，对于遴选适宜的治疗方案至关重要。然而，由于非白喉棒杆菌（non-diphtheriae Corynebacteria）的表型鉴定存在诸多难题，目前仍有不少菌株仅能被鉴定至属水平。故此，该研究方向的新探索将有助于我们加深对该棒杆菌属整体基础特性的认知，而不同棒杆菌物种间的比较分析则可揭示毒力基因，助力阐明其致病性。