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Number of truly associated independent loci discovered by HIPO, MTAG and individual trait analysis observed in datasets simulated under the covariance structure estimated from studies of blood lipids.

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Figshare2018-10-17 更新2026-04-29 收录
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See 1a-1d in S1 Table for detailed settings. We report the average number of truly associated loci identified by all the individual traits/HIPO components/MTAG estimates across 100 simulations, under significance threshold p −8 and LD pruning threshold r2 0.5Mb apart.

详细设置请见S1表(S1 Table)中的1a至1d小节。本研究报告了基于100次重复模拟实验的结果:在显著性阈值p=10^−8、连锁不平衡(Linkage Disequilibrium)修剪阈值设为r²=0.5且以0.5 Mb为间距进行筛选的条件下,所有单个性状、HIPO组分(HIPO)以及MTAG估计值(MTAG)所识别出的真实关联位点的平均数量。
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2018-10-17
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