Expression data from mouse adult and pups heart and hippocampal tissue.

To assess in order to assess potential disparities in gene expression due to developmental differences we performed a comparison between hippocampus and heart tissues from rat and mouse pup (one week old) and adult (10 week old) animals. Using heart and hippocampal tissue from mouse (C57BL/6) and rat (Sprague Dawley) we investigate via microarrays, gene expression divergence at the tissue level between a Brain and a Non-brain tissue. We also investigated any developement difference in gene expression between pups and adult animals. For the pups samples we used 3 biological replicates and for the adult samples we used 2 biological replicates with 2 technical replicates for each.

为评估发育差异导致的基因表达潜在差异，我们对大鼠和小鼠的1周龄幼崽与10周龄成年个体的海马体与心脏组织进行了对比分析。本研究采用C57BL/6品系小鼠及Sprague Dawley品系大鼠的心脏与海马组织，借助基因芯片（microarrays）技术，探究脑组织与非脑组织在组织层面的基因表达分化情况。同时，我们还分析了幼崽与成年动物间基因表达的发育差异。其中幼崽样本设置3个生物学重复，成年样本则设置2个生物学重复，且每个生物学重复搭配2个技术重复。