Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386

We report the genome sequence of <i>Streptomyces goldiniensis </i>ATCC 21386, a strain which produces the anti-bacterial and anti-virulence polyketide, aurodox. The genome of <i>S. goldiniensis </i>ATCC 21386 was sequenced using a multiplatform hybrid approach, revealing a linear genome of ~10 Mbp with a G+C content of 71 %. The genome sequence revealed 36 putative biosynthetic gene clusters (BGCs), including a large region of 271 Kbp that was rich in biosynthetic capability. The genome sequence is deposited in DDBJ/EMBL/GenBank with the accession number PRJNA602141.<br>These data represent the FastQ outputs from the Oxford Nanopore sequencing that contributed to the hybrid genome assembly.

本研究报道了<i>金迪链霉菌（Streptomyces goldiniensis）</i>ATCC 21386的基因组序列，该菌株可产生兼具抗菌与抗毒力活性的聚酮类化合物奥罗多克（aurodox）。本研究采用多平台混合测序策略对该菌株的基因组进行测序，结果显示其基因组为线性结构，全长约10 Mbp，G+C含量为71%。基因组序列分析共预测得到36个推定的生物合成基因簇（biosynthetic gene clusters, BGCs），其中包含一段长达271 Kbp、具备丰富生物合成功能的区域。该基因组序列已提交至DDBJ/EMBL/GenBank数据库，登录号为PRJNA602141。
本数据集包含用于该混合基因组组装的牛津纳米孔测序（Oxford Nanopore sequencing）所得的FastQ输出文件。