Characteristics of those with isolated (i-CNS) or combined (c-CNS) CNS relapses compared with those with an isolated bone marrow relapse (i-BM).

Relapses within 18 months of first diagnosis were termed as Very Early; after 18 months but within 6 months of stopping therapy as Early and after 6 months of stopping therapy as Late. B = progenitor B cell; T = T-cell; CSF = cerebrospinal fluid. CSF blast count is presented as cells/µl of CSF. Risk stratification and cytogenetic classification have previously been described.Characteristics of those with isolated (i-CNS) or combined (c-CNS) CNS relapses compared with those with an isolated bone marrow relapse (i-BM).

首次诊断后18个月内发生的复发被定义为极早期复发；首次诊断后18个月以上但停止治疗后6个月内发生的复发被定义为早期复发；停止治疗6个月以上发生的复发则被定义为晚期复发。B=前体B细胞（progenitor B cell）；T=T细胞（T-cell）；脑脊液（cerebrospinal fluid，简称CSF）。脑脊液原始细胞计数以每微升脑脊液中的细胞数为单位。风险分层及细胞遗传学分类方法既往已有文献报道。孤立性中枢神经系统复发（isolated CNS，简称i-CNS）、复合性中枢神经系统复发（combined CNS，简称c-CNS）患者与孤立性骨髓复发（isolated bone marrow relapse，简称i-BM）患者的临床特征对比。