Gene expression profile of MDA-MB-468 cell line over-expressing IGFBP2 gene

IGFBP2 is one of the putative biomarker of Afatinib response we identified. To dissect the biological processes sustained by IGFBP2 expression, we performed bulk 3' RNA-seq of MDA-MB-468 cell line over-expressing it Overall design: RNA-Seq

胰岛素样生长因子结合蛋白2（IGFBP2）是我们鉴定出的、与阿法替尼（Afatinib）应答相关的潜在生物标志物之一。为解析IGFBP2表达所维系的生物学过程，我们对过表达该蛋白的MDA-MB-468细胞系开展了批量3'端RNA测序。实验设计：RNA测序（RNA-Seq）。