SH1041528.10FU

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.

UNITE提供了一套统一的方法，用于界定、识别、交流以及处理基于DNA的物种假说（DNA-based Species Hypotheses，简称SH）。国际核酸序列数据库中的所有真菌内转录间隔区（Internal Transcribed Spacer，简称ITS）序列，通过应用一套动态距离阈值（0.5%~3.0%），被聚类至近似物种级别的单元。所有物种假说均会被赋予一个以数字对象标识符（Digital Object Identifier，简称DOI）为形式的唯一且稳定的名称，其分类学与生态学注释信息则通过分布式、基于网页的第三方注释工作完成验证。每个SH都会尽可能结合其包含的所有序列的鉴定结果，与一个分类单元名称及其所属的分类层级（门、纲、目等）建立关联。研究人员会选取一条经自动或人工指定的序列，作为每个SH的代表序列。这些代表序列会被发布至（https://unite.ut.ee/repository.php），供科学界用于本地序列相似性搜索以及下一代测序分析流程等科研场景。随着公共真菌ITS序列数量的持续增长，该系统及其配套数据会自动进行更新。