TNF mRNA steady state levels in unstimulated or LPS-stimulated FXR1-WT and KO macrophages untreated or treated with 4HPR.

Results are expressed as mean ± SEM of TNF mRNA relative expression level using FXR1-WT medium as calibrator. The p values were calculated using unpaired t-test.ap values refer to Medium versus 4HPR or LPS versus LPS & 4HPR group.bp values refer to FXR1-KO versus FXR1-WT macrophages.

结果以肿瘤坏死因子信使RNA（TNF mRNA）相对表达水平的平均值±标准误（SEM）表示，以FXR1-WT培养基作为校准参照。P值通过非配对t检验计算得出。注a：P值对应于培养基组与4HPR组，或脂多糖（Lipopolysaccharide, LPS）组与脂多糖联合4HPR组的组间比较。注b：P值对应于FXR1基因敲除型（FXR1-KO）巨噬细胞与FXR1野生型（FXR1-WT）巨噬细胞的组间比较。