Additional file 15 of Comparison between 5 extractions methods in either plasma or serum to determine the optimal extraction and matrix combination for human metabolomics

Additional file 15. Table S11. Summary of sensitivityfor labeled standard analytes across all extraction methods and LC-MS analyses. Sensitivity is given by the calibration curve slope, and the LOD and LOQ values are calculated as those corresponding to the signal-to-noise ratios of 3:1 and 10:1, respectively. The table displays a mean of LOD and LOQfor plasma vs. serum in each LC-MS conditions. Empty boxes stands not detected. LOD : limit of detection; LOQ : limit of quantitation; MeOH : methanol; MeOH:ACN : methanol combined with acetonitrile; ACN: acetonitrile; SPE : solid preparation extraction; ESI : electrospray ionisation; RP: reverse phase.

补充文件15：表S11。本表格汇总了所有萃取方法与液相色谱-质谱联用（liquid chromatography-mass spectrometry，LC-MS）分析中标记标准分析物的灵敏度。灵敏度以校准曲线斜率表征；检出限（LOD, limit of detection）与定量限（LOQ, limit of quantitation）分别以信噪比3:1与10:1为标准计算得到。表格展示了各LC-MS分析条件下，血浆与血清对应的LOD与LOQ的平均值。空白单元格代表未检出。相关缩写说明如下：MeOH为甲醇（methanol）；MeOH:ACN为甲醇与乙腈混合溶剂；ACN为乙腈（acetonitrile）；SPE为固相制备萃取（solid preparation extraction）；ESI为电喷雾电离（electrospray ionisation）；RP为反相色谱（reverse phase）。