Whole-genome comparison between group B streptococcus strains from infected newborns and their mothers

Streptococcus agalactiae, a commensal of the human gut and genitourinary tracts, is a major pathogen responsible for neonatal diseases in which the most frequent form of infection is vertical transmission from mother to child. Here, comparative genomics analyses were performed on 47 GBS strains obtained from 19 different pairs of infected neonates and their mothers.

无乳链球菌（Streptococcus agalactiae）是寄居人体肠道与泌尿生殖道的共生菌，同时也是引发新生儿疾病的主要病原菌，其最常见的感染途径为母婴垂直传播。本研究针对从19对感染新生儿及其母亲体内分离得到的47株B群链球菌（Group B Streptococcus, GBS）菌株开展了比较基因组学分析。