Microarray analysis comparing gene expression of callus tissue extracted from either Cyp24a1-null mice or their control heterozygous littermates

The 24R,25-dihydroxyvitamin D metabolite (24R,25D) has long been suspected of participating to bone fracture repair. We used Cyp24a1-deficient mice, unable to produce 24R25D, to observe gene expression in callus tissue compared to that of control littermates. In total 6 samples; 3 from Cyp24a1-null mice with the corresponding control littermate samples

24R,25-二羟基维生素D代谢物（24R,25-dihydroxyvitamin D metabolite，24R,25D）长期以来被推测参与骨折修复过程。本研究使用无法合成24R,25D的Cyp24a1缺陷型小鼠（Cyp24a1-deficient mice），对其骨痂组织中的基因表达进行观测，并与同窝对照小鼠的基因表达结果进行对比。本次实验共计6个样本：其中3个样本取自Cyp24a1基因敲除（Cyp24a1-null）小鼠，剩余样本为对应的同窝对照样本。