The Effect of Small Size Uterine Fibroids on Pregnancy Outcomes in High-risk Pregnancies

Abstract Objective To evaluate the obstetric outcomes of singleton high-risk pregnancies with a small size uterine fibroid. Methods This retrospective cohort study was conducted among 172 high-risk pregnant women who were followed-up by a single surgeon between 2016 and 2019. Pregnant women with preconceptionally diagnosed small size (< 5 cm) single uterine fibroids (n = 25) were compared with pregnant women without uterine fibroids (n = 147) in terms of obstetric outcomes. Results There was no statistically significant difference between the groups in terms of adverse pregnancy outcomes. The size of the fibroids was increased in 60% of the cases, and the growth percentage of the fibroids was 25% during pregnancy. Intrapartum and short-term complication was not observed in women who underwent cesarean myomectomy. Conclusion Small size uterine fibroids seem to have no adverse effect on pregnancy outcomes even in high-risk pregnancies, and cesarean myomectomy may be safelyperformed in properly selected cases.

摘要
研究目的：评估合并直径小于5cm单发子宫肌瘤（uterine fibroid）的高危单胎妊娠患者的产科结局。
研究方法：本回顾性队列研究纳入2016年至2019年间由同一位外科医师随访的172例高危孕妇。将孕前确诊为单发小子宫肌瘤（直径＜5cm，n=25）的孕妇与无子宫肌瘤的孕妇（n=147）的产科结局进行对比分析。
研究结果：两组患者的不良妊娠结局差异无统计学意义。60%的病例中子宫肌瘤体积出现增大，妊娠期肌瘤增长率为25%。接受剖宫产肌瘤剔除术的产妇未出现产时及短期并发症。
研究结论：即便在高危妊娠人群中，单发小子宫肌瘤似乎不会对妊娠结局产生不良影响，且在严格筛选合适病例的前提下，剖宫产肌瘤剔除术可安全实施。