Computational approach for the detection of evolutionarily conserved miRNA families in mammals

This study presents a systematic approach to analysis of mammalian miRNA families correlating with a genomic context that were retrieved in one of the more recent versions of miRBase. We explored both the annotation data of the miRNAs in families and the input data used in our computational procedure. Next, we identified and counted the mammalian conserved miRNA families.

本研究提出一套系统性分析方法，用于探究关联基因组背景的哺乳动物微RNA（microRNA）家族，相关数据检索自miRBase的较新版本之一。本研究同时考察了家族内微RNA的注释数据，以及本研究计算流程中所使用的输入数据。随后，本研究完成了哺乳动物保守型微RNA家族的识别与计数工作。