Form 12 – Injection Response Evaluation in Refractory Overactive Bladder: Sacral Neuromodulation v. Botulinum Toxin Assessment

Form 12 – Injection Response Evaluation, CSV Study Description The purpose of this randomized, open-label, active-control trial was to compare the effectiveness of intra-detrusor botulinum toxin A (Botox A®, Allergan) versus sacral neuromodulation (InterStim®, Medtronic) for the treatment of refractory urge urinary incontinence. In addition, the study evaluated select technical attributes of the interventions as well as the effect of these two interventions on other lower urinary tract and pelvic floor symptoms. Non-pregnant adult females at least 21 years old with refractory urinary urge incontinence表格12——注射反应评估，CSV格式 研究概述 本项随机、开放标签、阳性对照试验旨在比较膀胱内注射A型肉毒杆菌毒素（Botox A®，艾尔建公司）与骶神经调节疗法（InterStim®，美敦力公司）治疗难治性急迫性尿失禁的临床有效性。此外，本研究还评估了两种干预措施的部分技术属性，以及二者对其他下尿路及盆底症状的影响。受试对象为年龄≥21岁的非妊娠成年女性，且确诊为难治性急迫性尿失禁。