The crystal structure of the human carbonic anhydrase II in complex with an aliphatic bis-sulfamate inhibitor

The crystal structure of the human carbonic anhydrase II in complex with an aliphatic bis-sulfamate inhibitor Descriptor: 4-(HYDROXYMERCURY)BENZOIC ACID, CHLORIDE ION, Carbonic anhydrase 2, ... Authors: Alterio, V, De Simone, G. Deposit date: 2009-07-16 Release date: 2009-09-22 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis-sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors J.Med.Chem., 52, 2009

人碳酸酐酶II（Carbonic anhydrase II）与脂肪族双氨磺酰基抑制剂结合的晶体结构。描述符：4-(羟基汞基)苯甲酸、氯离子、碳酸酐酶2（Carbonic anhydrase 2）……。作者：阿尔泰里奥（V.）、德·西蒙尼（G.）。提交日期：2009年7月16日。发布日期：2009年9月22日。最后修改日期：2023年11月1日。实验方法：X射线衍射（2.2 Å）。引用文献：碳酸酐酶抑制剂：以脂肪族氨磺酰/双氨磺酰加合物与II型和IX型同工酶的结合为平台，设计高亲和力、同工酶选择性更强的抑制剂，J.Med.Chem., 52, 2009。