ToxicoDB: an integrated database to mine and visualize large-scale toxicogenomic datasets

This page links to the data associated with the publication "ToxicoDB: an integrated database to mine and visualize large-scale toxicogenomic datasets ". The data have been curated and analyzed using our open-source R package, ToxicoGx (https://github.com/bhklab/ToxicoGx) and are available publicly in the ToxicoDB web application (www.toxicodb.ca). Please see the included DOIs below, or download the .csv file which contains the names, dates and DOIs of all datasets listed here. The TGGATES data was generated by Igarashi Y, Nakatsu N, Yamashita T, Ono A, Ohno Y, Urushidani T, Yamada H. Open TG-GATEs: a large-scale toxicogenomics database. Nucleic Acids Res [Internet]. 2015 Jan;43(Database issue):D921–7. Available from: http://dx.doi.org/10.1093/nar/gku955 PMCID: PMC4384023.<br> <br> Data: TGGATEs human (https://doi.org/10.5281/zenodo.3762812) TGGATEs rat (https://doi.org/10.5281/zenodo.3762817) This Drug Matrix data was generated by Ganter B, Snyder RD, Halbert DN, Lee MD. Toxicogenomics in drug discovery and development: mechanistic analysis of compound/class-dependent effects using the DrugMatrix database. Pharmacogenomics [Internet]. 2006 Oct;7(7):1025–1044. Available from: http://dx.doi.org/10.2217/14622416.7.7.1025 PMID: 17054413. Data: Drug Matrix (https://doi.org/10.5281/zenodo.3766569)本页面关联了发表于论文《ToxicoDB：用于挖掘与可视化大规模毒基因组学数据集的整合型数据库》的相关数据。本数据集已通过我们的开源R包ToxicoGx（https://github.com/bhklab/ToxicoGx）完成整理质控与分析，可通过ToxicoDB网页应用（www.toxicodb.ca）公开获取。请参阅下文所列的数字对象标识符（DOI），或下载包含本页面所有数据集的名称、发布日期与DOI的.csv文件。 TGGATES数据集由Igarashi Y、Nakatsu N、Yamashita T、Ono A、Ohno Y、Urushidani T、Yamada H构建。相关论文：Open TG-GATEs：大规模毒基因组学数据库. 《核酸研究》[Nucleic Acids Res，网络版]. 2015年1月；43(数据库专辑)：D921–7. 可获取自：http://dx.doi.org/10.1093/nar/gku955 PMCID: PMC4384023。 数据集：人源TGGATEs（https://doi.org/10.5281/zenodo.3762812）、大鼠TGGATEs（https://doi.org/10.5281/zenodo.3762817）。 Drug Matrix数据集由Ganter B、Snyder RD、Halbert DN、Lee MD构建。相关论文：《药物发现与开发中的毒基因组学：基于DrugMatrix数据库的化合物/类别依赖性效应机制分析》. 《药物基因组学》[Pharmacogenomics，网络版]. 2006年10月；7(7)：1025–1044. 可获取自：http://dx.doi.org/10.2217/14622416.7.7.1025 PMID: 17054413。 数据集：Drug Matrix（https://doi.org/10.5281/zenodo.3766569）。