REDPET

he database includes taxonomic data to allow the assessment of the biodiversity of metagenomic libraries and a general functional analysis of genes using hidden Markov model (HMM) profiles based on the KEGG database. A set of 22 specialised HMM profiles was developed to detect putative genes for hydrocarbon-degrading enzymes. Use of these profiles showed that the metagenomic library generated after selection on crude oil had enriched genes for aerobic n-alkane degradation.

该数据库包含分类学数据，可用于评估宏基因组文库的生物多样性，并可基于京都基因与基因组百科全书（KEGG）数据库的隐马尔可夫模型（Hidden Markov Model）谱开展基因的通用功能分析。研究人员开发了一套共计22个专用HMM谱，用于检测烃降解酶的推定基因。应用这些谱图分析后发现，经原油筛选构建的宏基因组文库中，需氧正构烷烃降解相关基因得到了显著富集。