<p>Details of included studies.</p>

Introduction Malaria is a parasitic disease caused by Plasmodium parasite and transmitted to humans by infected female Anopheles mosquito. Several studies have explored community knowledge of malaria. However, despite the remarkable proportions of asymptomatic malaria, its awareness remains relatively understudied among the affected communities. Hence, this study aimed to determine the proportion of people with knowledge of asymptomatic malaria in endemic countries and describe their perspective towards malaria control interventions. The findings from this study could contribute to developing tailored interventions in both low and high-transmission settings. Method The systematic review protocol was deposited in protocols.io and registered at PROSPERO (ID: CRD42024508104). A systematic literature review was conducted searching for peer-reviewed articles on knowledge of asymptomatic malaria published from 2010 to 2024. Three databases (PubMed (MEDLINE), Google Scholar, and Web of Science) were searched. The risk of bias in the included studies was assessed using the Joanna Briggs Institute (JBI) critical appraisal tool and the Mixed Methods Appraisal Tool (MMAT). A thematic analysis and a narrative synthesis were conducted to synthesise the results. The research followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Results In total, 483 articles were retrieved, and 11 relevant articles were included in the analysis. According to four studies conducted among the general public, the proportion of individuals knowledgeable of asymptomatic malaria ranged from 14.2% to 79.8%. The proportion among health personnel was 88% (one study). The qualitative studies showed varied and lacking knowledge of asymptomatic malaria among the participants, as well as refusal and reluctance to adhere to interventions targeting asymptomatic Plasmodium carriers. Conclusion This review showed a lack of knowledge of asymptomatic malaria among endemic communities and a remarkable shortage of studies on related topics. For better malaria control and to accelerate disease elimination, education on asymptomatic malaria would be necessary. Given the limited number of studies, further research on knowledge of asymptomatic malaria would be crucial in various malaria-endemic areas to provide evidence for tailored interventions.引言 疟疾是由疟原虫（Plasmodium）引发的寄生虫病，通过受感染的雌性按蚊（Anopheles）传播至人类。已有多项研究探讨了社区对疟疾的认知情况，但尽管无症状疟疾的感染规模可观，受影响社区对其的认知仍相对缺乏充分研究。因此，本研究旨在明确疟疾流行地区人群中知晓无症状疟疾的比例，并描述其对疟疾防控干预措施的看法。本研究结果可为低、高传播场景下制定针对性干预措施提供参考。 方法 本研究的系统综述方案已提交至protocols.io平台，并在PROSPERO平台注册（注册号：CRD42024508104）。本研究开展了系统文献检索，检索了2010年至2024年间发表的关于无症状疟疾认知的同行评议文献，检索数据库包括PubMed（MEDLINE）、Google Scholar及Web of Science。采用乔安娜·布里格斯研究所（Joanna Briggs Institute, JBI）关键评价工具与混合方法评价工具（Mixed Methods Appraisal Tool, MMAT）对纳入研究的偏倚风险进行评估。通过主题分析与叙事合成法对研究结果进行整合。本研究遵循系统综述与元分析首选报告条目（Preferred Reporting Items for Systematic Reviews and Meta-Analyses, PRISMA）规范开展。 结果 本研究共检索到483篇文献，最终纳入11篇相关文献进行分析。针对普通人群的4项研究显示，知晓无症状疟疾的人群比例介于14.2%至79.8%之间。针对医护人员的1项研究显示其知晓比例为88%。定性研究结果表明，受试者对无症状疟疾的认知参差不齐且普遍不足，同时存在拒绝或不愿依从针对无症状疟原虫携带者的干预措施的情况。 结论 本综述显示，疟疾流行社区对无症状疟疾的认知普遍不足，且相关主题的研究数量显著匮乏。为优化疟疾防控工作、加速疾病消除进程，普及无症状疟疾相关知识十分必要。鉴于现有研究数量有限，在各类疟疾流行地区进一步开展无症状疟疾认知相关研究，可为制定针对性干预措施提供循证依据，这一点至关重要。