Differentially expressed genes in same sex comparisons between knockout and wildtype tadpole gonads for X. laevis dmrt1.

S and dmrt1.L lines using counts from Kallisto and analysis with DeSeq2 (Analysis 2). The four analyses performed include comparisons of female or male dmrt1S knockouts to same-sex wildtypes (dmrt1.S females, dmrt1.S males, respectively) and comparisons of female or male dmrt1.L knockouts to same-sex wildtypes (dmrt1.L females, dmrt1.L males, respectively). Negative log2 fold change (logFC) means expression is higher in the wildtype compared to the knockout; positive values indicate the opposite. Other informatiojn includes the log fold change standard error (lfcSE), Stat is the logFC/lfcSE; the p value (PValue) and Benjamini-Hochberg adjusted p valuie (padj), the chromosome and subgenome for each gene, the gene acronym for Xenopus (Xen_acro) and humans (Hum_acro), and whether each differentially expressed gene was also sex-biased (SB?) in an analysis performed by Cauret et al. 2023. (XLSX)

本分析（分析2）基于Kallisto的定量计数结果，针对S品系与dmrt1.L品系开展统计分析，共完成四项比对：分别将雌性或雄性dmrt1.S基因敲除组与同性野生型组进行比较（对应组别为dmrt1.S雌性敲除组、dmrt1.S雄性敲除组），以及将雌性或雄性dmrt1.L基因敲除组与同性野生型组进行比较（对应组别为dmrt1.L雌性敲除组、dmrt1.L雄性敲除组）。负对数2倍变化值（log₂FC）表示野生型组的基因表达水平高于敲除组，正值则代表相反情况。其余数据集信息包括：对数倍变化标准误（lfcSE）、统计量Stat（即log₂FC与lfcSE的比值）、原始P值（PValue）、经Benjamini-Hochberg方法校正的P值（padj）、每个基因所在的染色体与亚基因组、爪蟾属（Xenopus）基因缩写（Xen_acro）与人类基因缩写（Hum_acro），以及各差异表达基因是否在Cauret等人2023年的一项分析中呈现性别偏向性（SB？）。本数据集以XLSX格式存储。