Additional file 2 of Limited evidence for blood eQTLs in human sexual dimorphism

Additional file 2: Table S1. Sex-specific eQTLs. Table S2. Summary statistics for eQTLs in binding sites for estrogen receptor genes. Table S3. Gene level summary statistics. Table S4. Wilcoxon test P-values for mean sex differences in cellular composition. Table S5. Wilcoxon test P-values for mean sex differences in principal components. Table S6. Levene test P-values for mean sex differences before and after correcting for principal components. Table S7. BIOS results for the sex-biased eQTLs found in Yao et al [PMID: 24242183]. Table S8. BIOS results for the sex-biased eQTLs found in Kukurba et al [PMID: 27197214]. Table S9. Replication analyses results - SHIP-Trend cohort. Table S10. PheWAS for top sex-specific eQTLs. Table S11. Independent SNPs associated with WHR. Table S12. Independent SNPs associated with testosterone. Table S13. Sex-stratified TWMR results for testosterone. Table S14. Sex-stratified TWMR results for WHR. Table S15. Sex specific causal genes for WHR and testosterone.

附加文件2：表S1：性别特异性表达数量性状位点（expression quantitative trait locus, eQTL）。表S2：雌激素受体基因结合位点中eQTL的汇总统计量。表S3：基因层面汇总统计量。表S4：细胞组成平均性别差异的威尔科克森检验P值。表S5：主成分平均性别差异的威尔科克森检验P值。表S6：校正主成分前后平均性别差异的莱文检验P值。表S7：Yao等人[PMID: 24242183]发现的性别偏向性eQTL的BIOS分析结果。表S8：Kukurba等人[PMID: 27197214]发现的性别偏向性eQTL的BIOS分析结果。表S9：重复分析结果——SHIP-Trend队列。表S10：顶级性别特异性eQTL的全表型组关联研究（phenome-wide association study, PheWAS）。表S11：与腰围身高比（waist-to-hip ratio, WHR）相关的独立单核苷酸多态性（single nucleotide polymorphism, SNP）。表S12：与睾酮相关的独立SNP。表S13：睾酮的性别分层转录组全范围孟德尔随机化（transcriptome-wide Mendelian randomization, TWMR）结果。表S14：WHR的性别分层TWMR结果。表S15：WHR与睾酮的性别特异性因果基因。