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Structural Insights into the Extracellular Recognition of the Human Serotonin 2B Receptor by an Antibody

NIAID Data Ecosystem2026-05-02 收录

血清素受体

抗体-受体互作

数据链接：

https://www.rcsb.org/structure/5TUD 数据链接链接失效反馈

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Structural Insights into the Extracellular Recognition of the Human Serotonin 2B Receptor by an Antibody

抗体对人类5-羟色胺2B受体（Serotonin 2B Receptor）胞外识别的结构解析

应用场景：

创建时间：

2024-10-30

血清素受体

精神药物机制

Fluoxetine (Prozac) inhibited the membrane currents elicited by serotonin (5-hydroxytryptamine; 5HT) in Xenopus oocytes expressing either cloned 5HT(2C) receptors or 5HT receptors encoded by rat corte

PubMed Central1997-03-04 更新40

Structure-Based Scaffold Repurposing for G Protein-Coupled Receptors: Transformation of Adenosine Derivatives into 5HT 2B /5HT 2C Serotonin Receptor Antagonists

血清素受体

药物发现

Adenosine derivatives developed to activate adenosine receptors (ARs) revealed micromolar activity at serotonin 5HT2B and 5HT2C receptors (5HTRs). We explored the structure–activity relationship at 5H

NIAID Data Ecosystem30

Data from: Effects of population structure and sex on association between serotonin receptors and Drosophila heart rate

果蝇遗传学

血清素受体

As a first step toward population and quantitative genetic analysis of neurotransmitter receptors in Drosophila melanogaster, we describe the parameters of nucleotide variation in three serotonin rece

DataONE2009-05-20 更新30

Table S1 - Serotonin Receptor Expression in Human Prefrontal Cortex: Balancing Excitation and Inhibition across Postnatal Development

血清素受体

前额叶皮层

Demographic details of cases used in this study. Abbreviations: m, male; f, female; PMI, post-mortem interval defined as interval between death and freezing of the brain; AA, African American; C, Cauc

NIAID Data Ecosystem40

Active Metabolite of Aeruginascin (4-Hydroxy‑ N , N , N ‑trimethyltryptamine): Synthesis, Structure, and Serotonergic Binding Affinity

神经药理学

血清素受体

The putative active metabolite of aeruginascin, a naturally occurring tryptamine of “magic mushrooms,” has been synthesized and structurally characterized. Competitive radioligand binding assays demon

NIAID Data Ecosystem30

Structural Insights into the Extracellular Recognition of the Human Serotonin 2B Receptor by an Antibody

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