proteomics analysis of small extracellular vesicles from mouse liver tissue across age groups

The project aims to investigate the proteomic changes in small extracellular vesicles (sEVs) derived from mouse liver tissue across different age groups to identify proteins associated with aging. The study employs a comprehensive proteomic analysis to reveal age-dependent alterations in protein expression, which could provide insights into the molecular mechanisms of aging and potentially identify biomarkers for age-related diseases.

本项目旨在探究不同年龄组小鼠肝组织来源的小细胞外囊泡（small extracellular vesicles, sEVs）中的蛋白质组学变化，以鉴定与衰老相关的蛋白质。本研究采用全面蛋白质组学分析，揭示蛋白质表达的年龄依赖性改变，可为衰老的分子机制提供研究见解，并有望筛选出年龄相关疾病的生物标志物。