14alpha-demethylase (CYP51) with amide-linked long arm extension antifungal azole inhibitor
收藏Protein Data Bank Japan2025-07-30 更新2026-06-30 收录
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https://pdbj.org/mine/summary/8vk6
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14alpha-demethylase (CYP51) with amide-linked long arm extension antifungal azole inhibitor Descriptor: DODECYL-BETA-D-MALTOSIDE, Lanosterol 14-alpha demethylase, N-[(2S)-2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]-4'-(trifluoromethoxy)[1,1'-biphenyl]-4-carboxamide, ... Authors: Tyndall, J.D.A, Monk, B.C, Simons, C. Deposit date: 2024-01-08 Release date: 2025-01-15 Last modified: 2025-07-30 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Exploring Long Arm Amide-Linked Side Chains in the Design of Antifungal Azole Inhibitors of Sterol 14 alpha-Demethylase (CYP51). J.Med.Chem., 68, 2025
创建时间：
2024-01-08
