Marker genes for cardiac cell types in <i>Tabula Muris</i>.

Shown are marker genes identified for each cluster using the FindAllMarkers function in Seurat. Column A and B report the gene name and tested cell type, respectively; column C represents the % of cells labeled as the cell type described in column B that express the gene; column D represents the % of cells in all other cell types that express the same gene; column E shows the log2 fold change between the average expression level in the cell type described in column B and all other cells; column F and G represent the p-value (Wilcoxon rank sum test) and FDR-adjusted p-value (Bonferroni). All values described in this table were calculated using the FindAllMarkers function in Seurat with parameters min.pct = 0.2, logfc.threshold = 0.1. Only genes with FDR < 0.1 are shown. If a gene is significantly overexpressed in more than one cell type, it is reported multiple times. (CSV)本研究通过Seurat包中的FindAllMarkers函数鉴定得到各细胞簇的标志性基因。A列与B列分别记录基因名称与所检测的细胞类型；C列为B列所述细胞类型中表达该基因的细胞占比；D列为其余所有细胞类型中表达该基因的细胞占比；E列为B列所述细胞类型与其余所有细胞的平均表达量的log₂倍变化值；F列与G列分别代表通过Wilcoxon秩和检验得到的P值，以及经Bonferroni校正的错误发现率（FDR）校正P值。本表格中所有数值均通过Seurat包的FindAllMarkers函数计算得到，所用参数为min.pct = 0.2、logfc.threshold = 0.1。仅展示FDR < 0.1的基因。若某一基因在多种细胞类型中均显著高表达，则会被多次记录。(CSV)