Frequencies of <i>IL10</i> −2849/−1082/−819 promoter haplotypes and comparisons between subgroups.

Only haplotypes with frequencies >0.01 are given. The reference haplotype GGC is associated with the highest IL-10 production with the following haplotypes ordered according to their presumed decreasing IL-10 production [25]. The variant occurring at position −592 may in all cases be inferred from those at postions −1082 and −819. n, estimated counts of inferred haplotypes in cases and controls; PPD+, PPD-positive, PPD−, PPD-negative; OR, estimated odds ratios of a haplotype, compared to the reference haplotype; CI, 95% confidence interval. pglobal refers to the overall likelihood ratio test of association; pglobal/corr represents adjusted P values after 10 000 permutations.仅保留频率大于0.01的单倍型（haplotype）。参考单倍型GGC与最高水平的白细胞介素10（IL-10）产生相关，后续单倍型按照其推定的IL-10产生能力从高到低排序[25]。位于−592位点的变异在所有情况下均可通过−1082和−819位点的变异推断得到。 n：病例组与对照组中推断得到的单倍型的估计计数；PPD+：PPD阳性（PPD-positive），PPD−：PPD阴性（PPD-negative）；OR：以参考单倍型为对照的单倍型比值比估计值；CI：95%置信区间（95% confidence interval）。pglobal指代关联分析的整体似然比检验结果；pglobal/corr表示经10000次置换校正后的校正P值。